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临床前研究表明，骨髓来源的巨噬细胞（Bone Marrow Derived Macrophage，BMDM)的注射能够减轻炎症、消除纤维化并促进肝组织再生 [1,2]，而今年在Nature Medicine发表的研究成 …
Here, we describe a procedure to isolate and cultivate macrophages from murine bone marrow that will provide large numbers of macrophages for studying host-pathogen interactions as well …
BMDM是原代细胞和有生物功能的巨噬细胞和单核细胞分化的性能，因为有成熟，而相比之下，巨噬细胞的细胞系，这是不成熟。 BMDMs可用于遗传筛查（RNAi）技术，药物筛选，功能研 …
Feb 22, 2021 · Here, we show that fructose reprograms cellular metabolic pathways to favour glutaminolysis and oxidative metabolism, which are required to support increased …
Oct 28, 2024 · Fructose is associated with colorectal cancer tumorigenesis and metastasis through ketohexokinase-mediated metabolism in the colorectal epithelium, yet its role in the …
Sep 8, 2023 · 在这项工作中，我们成功地永生化并扩增了骨髓来源的小鼠巨噬细胞（BMDM），该巨噬细胞可用作研究与肿瘤细胞共培养中的吞噬作用和极化的工具。
Mar 19, 2021 · This protocol describes the collection of bone marrow cells from the femur and tibia of mice, differentiation into bone marrow-derived macrophages (BMDM cells), and sampling …
Oct 30, 2024 · 上海交通大学研究团队在探究糖酵解重编程在调节巨噬细胞极化和细胞焦亡背后的具体机制相关研究中，使用RFect siRNA转染试剂将靶向糖酵解途径中必需的酶PGK1 …
Dec 1, 2018 · To investigate the functions of fructokinase (FRK) in apple (Malus domestica) carbohydrate metabolism, we cloned the coding sequences of MdFRK1 and MdFRK2 from the …
Dec 31, 2020 · This protocol focuses on the efficient preparation of BMDM cells, providing a way to assess the function of macrophages. For complete details on the use and execution of this …
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